Work

CD30/CD30 Ligand and CD40/CD40 Ligand in Malignant Lymphoid Disorders

Year: 1999

Type: review

Abstract: CD30 and CD40 are members of the tumor necrosis factor (TNF) receptor family. These two receptors have pleiotropic biologic functions including induction of apoptosis and enhancing cell survival. This review will discuss the pattern of expression of these receptors in malignant lymphoid disorders and their prospective ligands. Understanding issues related to these two ligands and their receptors in lymphoid malignancies may help to improve the classification of these diseases and could open the doors for new treatment strategies.

Source: The International Journal of Biological Markers

DOI: 10.1177/172460089901400303

Authors: A. Younes, A. Carbone

Institutions: The University of Texas MD Anderson Cancer Center, Centro di Riferimento Oncologico

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Associazione Italiana per la Ricerca sul Cancro