Work

[Angiotensin-converting enzyme inhibitors :from vasoactive drugs to cardiovascular prevention tools].

Year: 2003

Type: article

Abstract: Abundant evidence showed that angiotensin-converting enzyme (ACE)-inhibitors reduce long-term cardiovascular morbidity and mortality rates in patients with heart failure and myocardial infarction. More recent studies revealed clinical benefits also in hypertensive patients with comorbidity and lead to an extension of clinical indications. Indeed in patients with severe hypertension differences between drugs are hardly detectable because the risk reduction is mainly related to the control of blood pressure values independent of the type of therapy. Conversely in the presence of comorbid conditions, especially in diabetics, the association of ACE-inhibitors with antihypertensive treatments proved its efficacy in reducing cardiovascular morbidity and mortality so that the role of mechanisms extending beyond blood pressure reduction can be postulated.

Source: PubMed

Authors: Pietro Amedeo Modesti, Simone Vanni, Gian Franco Gensini

Institutions: University of Florence, Don Carlo Gnocchi Foundation

Language: Italian

Topic: Renin-Angiotensin System Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2398476061

FWCI:

Cites: 100

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Related to: 10