The simultaneous presence of Langerhans' cell and interdigitating cell antigenic markers on inflammatory dendritic cells.
Year: 1986
Type: article
Study design: Observational Study
Abstract: Immunohistological studies have been performed on tissues from various dermatological conditions using two monoclonal antibodies, RFD1 and NA1/34. These reagents were used to determine whether antigen expression restricted to interdigitating cells (RFD1+) and Langerhans' cells (NA1/34+) in normal tissues might occur together on dendritic cells involved in cutaneous inflammatory reactions. The results presented demonstrate that in psoriasis, allergic contact dermatitis and atopic dermatitis a proportion of the inflammatory dendritic cells express both antigens.
Source: PubMed
Authors: V A Alegre, D M MacDonald, L W Poulter
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2398739551