Year: 1973
Type: article
Abstract: The localization, isolation and partial characterization of a collagenolytic enzyme from the land planarian Bipalium kewense is described. This enzyme can be obtained by direct extraction of the organism, and can be separated from non-collagenous proteolytic activity by (NH(4))(2)SO(4) precipitation and Sephadex-gel chromatography. Its mode of attack on collagen and sensitivity to a variety of inhibitors indicate that this enzyme differs from vertebrate collagenases and a previously described invertebrate collagenase.
Source: Biochemical Journal
DOI: 10.1042/bj1330329
Authors: J. Phillips, M. H. Dresden
Institution: Baylor College of Medicine
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: bronze
Funders: Welch Foundation, Rice University
OpenAlex ID: W2399386848