Work

Real-time simultaneous single snapshot of optical properties and blood flow using coherent spatial frequency domain imaging (cSFDI)

Year: 2016

Type: article

Abstract: In this work we present and validate a wide-field method for the real-time mapping of tissue absorption, scattering and blood flow properties over wide regions of tissue (15 cm x 15 cm) with high temporal resolution (50 frames per second). We achieve this by applying Fourier Domain demodulation techniques to coherent spatial frequency domain imaging to extract optical properties and speckle flow index from a single snapshot. Applying this technique to forearm reactive hyperemia protocols demonstrates the ability to resolve intrinsic physiological signals such as the heart beat waveform and the buildup of deoxyhemoglobin associated with oxygen consumption.

Source: Biomedical Optics Express

DOI: 10.1364/boe.7.000870

Authors: Michael Ghijsen, Bernard Choi, Anthony J. Durkin, Sylvain Gioux, Bruce J. Tromberg

Institutions: University of California, Irvine, Beckman Laser Institute and Medical Clinic, University of California, Irvine Medical Center, Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie, Université de Strasbourg

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $1,913