A case of diabetic ketoacidosis associated with long-term risperidone use
Year: 2009
Type: article
Study design: Case Report
Abstract: The atypical antipsychotics used to treat patients with schizophrenia may cause many metabolic problems, such as weight gain, hyperlipidemia, diabetes mellitus (DM) and, rarely, diabetic ketoacidosis (DKA). We report the first case of new-onset type 2 DM and DKA associated with long-term risperidone use in Korea. A 42-year-old man visited our hospital complaining of polydipsia, polyuria, polyphagia, generalized weakness, and weight loss. He had been taking risperidone (4 mg/day) to treat schizophrenia for 7 years. Based on laboratory tests, dyslipidemia and new-onset type 2 DM accompanied by DKA were diagnosed. He was treated immediately with intravenous hydration and insulin therapy, and recovered completely. When treating patients with risperidone, it is important to monitor their weight, blood pressure, fasting blood glucose, and lipid profile carefully because risperidone may lead to type 2 DM or, rarely, DKA. (Korean J Med 77:S1212-S1216, 2009)
Institution: Hallym University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W2401086581