Work

Contemporary Understanding and Management of Overt and Covert Hepatic Encephalopathy.

Year: 2016

Type: article

Abstract: Hepatic encephalopathy (HE) is a major complication of liver disease that leads to significant morbidity and mortality. Caring for hospitalized patients with HE is becoming more complex, and the economic burden of HE continues to rise. Defining and diagnosing HE, particularly covert HE (CHE), remain challenging. In this article, we review new tools and those currently under development for the diagnosis of CHE and the latest advances in the acute and long-term management of overt HE (OHE) and CHE. In particular, we review the latest data on the use of lactulose and rifaximin for treatment of OHE and summarize the data on adjunctive agents such as sodium benzoate and probiotics.

Source: PubMed

Authors: Meghan NeSmith, Joseph Ahn, Steven L Flamm

Institutions: Northwestern University, Oregon Health & Science University, University of Portland

Language: English

Topic: Liver Disease and Transplantation

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2401590119

FWCI: 1.736

Cites: 47

Cited by: 15

Related to: 10