Work

Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft

Year: 2016

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2016.05.065

Authors: Bradley R. Kossmann, Monica Abdelmalak, Sophia Lopez, Gabrielle Tender, Chunli Yan, Yves Pommier, Christophe Marchand, Ivaylo Ivanov

Institutions: Georgia State University, National Institutes of Health, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Cancer therapeutics and mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, Office of Science, National Cancer Institute, National Institute of General Medical Sciences

Awards: G1099829771, CAREER: Modeling Assemblies and Interactions at the Replication Fork: Sliding Clamps and Clamp Loaders, G419881185, Integrative modeling of PCNA assemblies engaged in genome duplication and repair, G6374948078, G9000020722

OpenAlex ID: W2402540491

FWCI: 1.053

Cites: 25

Cited by: 14

Related to: 10