Work

3D protein structure prediction of influenza A virus based on optimization genetic algorithm

Year: 2014

Type: article

Abstract: The 3D structure of close polymer is constituted by the interaction of close contact couples among amino acid residues. In this paper, 3D protein structure of influenza A virus was predicted. Twenty kinds of amino acid residues were divided into four categories according to the number of close contact couples. The stable structure with minimum energy was obtained by using optimization genetic algorithm. The HNXP 3D lattice model was established to predict the 3D protein structure. It can be concluded that the two kinds of structures are significantly similar by computing the similarity.

Source: Pakistan Journal of Pharmaceutical Sciences

DOI: 10.36721/pjps/27/3(sup)/2014/41/735-739

Author: Jie Gao

Institution: Jiangnan University

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Fundamental Research Funds for the Central Universities

Awards: p53抑癌基因分子调控机制的数学建模及其算法研究, G6443193093