Work

Implementation of Molecular Surveillance After a Cluster of Fatal Toxoplasmosis at 2 Neighboring Transplant Centers

Year: 2016

Type: article

Study design: Observational Study

Abstract: After a cluster of fatal toxoplasmosis among stem cell transplant recipients at 2 hospitals, surveillance with polymerase chain reaction (PCR) (blood) was instituted. Rate of reactivation among seropositive recipients was 2.2 and 16%. Parasitemia was successfully managed with preemptive treatment. For seropositive recipients unable to take prophylaxis, toxoplasma PCR surveillance should be routinely performed.

Source: Clinical Infectious Diseases

DOI: 10.1093/cid/ciw330

Authors: Flonza Isa, Kohta Saito, Yao-Ting Huang, Audrey Schuetz, N. Esther Babady, Steven Salvatore, Melissa Pessin, Koen van Besien, Miguel-Angel Perales, Sergio Giralt, Kent Sepkowitz, Genovefa A. Papanicolaou, Rosemary Soave, Mini Kamboj

Institutions: Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Toxoplasma gondii Research Studies

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences

Awards: Clinical and Translational Science Center, Cancer Center Support Grant, Clinical and Translational Science Center, Research Training in Infectious Diseases

OpenAlex ID: W2404674172

FWCI: 4.126

Cites: 12

Cited by: 25

Related to: 10