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Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics

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Year: 2016
Type: article
Source: NeuroMolecular Medicine
DOI: 10.1007/s12017-016-8412-z
Authors: Jing Jin, Hao Gu, Nicole M. Anders, Tianhua Ren, Mali Jiang, Michael Tao, Qi Peng, Michelle A. Rudek, Wenzhen Duan
Institutions: Johns Hopkins University, Johns Hopkins Medicine, Sidney Kimmel Comprehensive Cancer Center, Capital Medical University, Beijing Tian Tan Hospital
Language: English

Topic: Genetic Neurodegenerative Diseases
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Johns Hopkins University, National Institutes of Health, Sidney Kimmel Comprehensive Cancer Center, Sidney Kimmel Center for Prostate and Urologic Cancers, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Center for Research Resources, National Center for Advancing Translational Sciences
Awards: UPLC with Tandem MS for Sensitive Quantitative Analysis of Small Molecules, Huntington's disease biomarkers and therapeutics, Institute for Clinical and Translational Research, Regional Oncology Research Center
OpenAlex ID: W2407471740
FWCI: 2.365
Cites: 29
Cited by: 49
Related to: 10
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