Safety and Efficacy Study of Herbal Polyphyto Formulations: for Its Learning and Memory Enhancing Properties
Year: 2016
Type: article
Abstract: Objective: The present study was designed to evaluate the effectiveness of the poly photo formulation for its learning and memory activity. Methods : The Indian origin test drug, FM7 phyto formulation compose of Convolulus pluricaulis , Habiscus rosasinnsis , Withania somnifera , Terminalia arjuna and Emblica officinalis , having the potential effect to improving memory studied at a dose of 50 mg and 100 mg/kg p. o. by using three different animal model like Elevated plus maze (EPM), Morris water maze (MWM) and Pole Climbing apparatus (PCA) for the effect of nootropic action; against standard drug Bacopa monnieri evaluated on the basis of transfer latency reduction on a rat, before and after drug administration. Results: On treatment with polyherbal formulation FM7 showed a significant effect on enhancing learning and memory properties. It was observed that significant (p<0.001) reduction in transfer latency in Elevated Plus Maze, Morris Water Maze test and escape latency in Pole Climbing Apparatus test as compared with the control; as well as standard Bacopa monnieri . Conclusion : The polyphyto formulation FM7 composed of ( Convolulus pluricaulis 20% , Habiscus rosasinnsis 20% , Withania somnifera 20% , Terminalia arjuna 20% and Emblica officinalis 20% ) found to be safe and effective in enhancing learning and memory properties. Keywords: Learning and memory, Convolulus pluricaulis, Phyllanthus Emblica, Withania somnifera, Habiscus rosasinnsis, Terminalia arjuna
Institution: Uttarakhand Technical University
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2407748525