Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor.
Year: 1997
Type: article
Source: PubMed
Authors: J K Burkhardt, S Hüttler, A Klein, W Möbius, A Habermann, G Griffiths, K Sandhoff
Language: English
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W2409723636