Work

MicroRNAs in normal and cancer cells: a new class of gene expression regulators.

Year: 2006

Type: article

Abstract: MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression at posttranscriptional level. They are involved in cellular development, differentiation, proliferation and apoptosis and play a significant role in cancer. This review describes miRNA biogenesis, their functions in normal cells, and alterations of miRNA sets in cancer and roles of antitumorigenic and oncogenic miRNAs in cancer development.

Source: PubMed

Authors: T V Bagnyukova, I P Pogribny, V F Chekhun

Institution: Vasyl Stefanyk Carpathian National University

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Oak Ridge Institute for Science and Education

OpenAlex ID: W2410695820

FWCI: 1.018

Cites: 77

Cited by: 24

Related to: 10