Effects of two kinds of radio frequency ablations on morphology and function of left atrium in patients with atrial fibrillation.
Year: 2015
Type: article
Abstract: OBJECTIVE: This study aims to observe the effects of circumferential pulmonary vein ablation (CPVA) and CPVA combined with complex fractionated atrial electro-gram (CPVA+CFAE) on morphology and function of left atrium in patients with atrial fibrillation (AF). METHODS: To evaluate the effects of CPVA and CPVA+CFAE on morphology and function of left atrium, the left atrial volume and late diastolic velocity peak (Va) were determined by tissue Doppler imaging before and after CPVA and CPVA+CFAE, respectively. RESULTS: There was no statistical difference in the left atrial volume before and after CPVA. However, Va was significantly higher after CPVA (P=0.001). There was no statistical difference in both the left atrial volume and Va before and after CPVA+CFAE. Va after ablation was significantly higher in CPVA group than in CPVA+CFAE group (P=0.031). CONCLUSION: The left atrial function was significantly improved after CPVA, but CPVA+CFAE failed to markedly improve the left atrial function. This suggests that excessive atrial substrate ablation may damage the left atrial function.
Source: PubMed
Authors: Gang Lin, Xiang-Jun Yang
Institution: First Affiliated Hospital of Soochow University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2411963858