Work

Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With bOPV or IPV

Year: 2016

Type: article

Abstract: BACKGROUND: Vaccine schedules including bivalent oral and inactivated poliovirus vaccines will replace trivalent oral poliovirus vaccines in 2016. METHODS: We evaluated rotavirus immunoglobulin A seroresponses when the second dose of Rotarix at 16 weeks was given concomitantly with inactivated or bivalent oral poliovirus vaccines. RESULTS: Rotavirus immunoglobulin A seroresponse rate at week 28 was 15% lower in recipients of bivalent oral poliovirus vaccines compared with inactivated poliovirus vaccines. CONCLUSION: Bivalent oral poliovirus vaccine decreases rotavirus IgA seroresponse rates when coadministered at 16 weeks of age.

Source: The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0000000000001253

Authors: Sasirekha Ramani, Nora Mamani, Rodolfo Villena, Ananda S. Bandyopadhyay, Chris Gast, Alicia Sato, Daniel Laucirica, Ralf Clemens, Mary K. Estes, Miguel L. O’Ryan

Institutions: Gates Foundation, Baylor College of Medicine, Fred Hutch Cancer Center, Hospital Dr. Exequiel González Cortés, University of Chile

Language: English

Topic: Viral gastroenteritis research and epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2414747688

FWCI: 4.921

Cites: 15

Cited by: 32

Related to: 10