Organ and species specificity of rat hepato-cellular antigens.
Year: 1966
Type: article
Abstract: The organ and species specificity of rat hepato-cellular antigens has been studied. Lung and heart share a common group of antigens with the kidney and liver, while the kidney contains those antigens in common with the liver which are not present in either lung or heart. Absorption of anti-rat liver serum with rat kidney conferred on it strict specificity for the antigens present within the cytoplasm of the rat hepatic parenchymal cell. The results obtained from the study of the species distribution of the organ specific hepato-cellular antigens suggest that each animal species is characterized by the presence of species specific hepatic antigens, in addition to which there exists a group of antigens which cross species barriers and are present in all species investigated.
Source: PubMed
Authors: A U Sargent, J Myers, B Rose, M Richter
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2416454767