Work

Hyperuricemia as a Potential Determinant of Metabolic Syndrome.

Year: 2013

Type: article

Abstract: Recent studies have focused on hyperuricemia as a modulator for metabolic syndrome. Hyperuricemia has reported in many studies as a causal marker in a higher prevalence of metabolic syndrome. In fact, insulin resistance, dyslipidemia, obesity and hypertension, each of these variables of metabolic syndrome gets influenced by the serum uric acid level. High level of uric acid has been associated with metabolic syndrome, type 2 diabetes and cardiovascular diseases. Hyperuricemia has attributed to hyperinsulinemia in metabolic syndrome and decreased excretion of uric acid causing endothelial dysfunction in kidney leads to renal disease and cardiovascular disorders. This review focus on the role of uric acid in the development of metabolic syndrome and onthe possible pathophysiology.

Source: Europe PMC (PubMed Central)

Authors: Dhananjay Yadav, Eun Soo Lee, Hong Min Kim, Eun Young Lee, Eunhee Choi, Choon Hee Chung

Institutions: Yonsei University, Yonsei University Mirae Campus, Soonchunhyang University, Soonchunhyang University Hospital Cheonan

Language: English

Topic: Gout, Hyperuricemia, Uric Acid

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Research Foundation of Korea, Ministry of Education, Science and Technology

OpenAlex ID: W2416750602

FWCI: 0.234

Cites: 96

Cited by: 21

Related to: 10