Year: 2015
Type: dissertation
Abstract: The purpose of this investigation was to assess the impact of anisometropic amblyopia, a neurodevelopmental disorder of vision, on sensorimotor control. This was accomplished by adapting the manual motor system to a change in the spatial environment resulting from the placement of bilateral 20 D left-shifting wedge prisms in front of the eyes. During prism adaptation, participants initially missed the target in the direction of optical displacement but in the presence of visual feedback and with repeated pointing, they were able to adapt to this perturbation. Eleven visually-normal control participants and seven people with anisometropic amblyopia were tested binocularly on this task. People with anisometropic amblyopia displayed a significantly longer time course of adaptation than visually-normal controls, with higher variability during the strategic recalibration phase of adaptation. It is suggested that increased visual variability, temporal synchrony deficits and deficits in extra-striate visual processing in amblyopia contribute to the above findings.
Source: TSpace (University of Toronto)
Author: Jaime C. Sklar
Language: English
Topic: Motor Control and Adaptation
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2419070779