Antibacterial activity of Taxodium ascendens Diterpenes against Methicillin-resistant Staphylococcus aureus
Year: 2014
Type: article
Abstract: One new and seven known diterpenes were identified from an antibacterial chromatographic fraction of Taxodium ascendens. Of these, demethylcryptojaponol (2), 6-hydroxysalvinolone (3), hydroxyferruginol (4), and hinokiol (5) demonstrated potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). These compounds represent a class of synthetically accessible compounds that could be further developed for treatment of drug-resistant bacterial infections.
Source: Natural Product Communications
Authors: Courtney M. Starks, Vanessa L. Norman, Russell B. Williams, Matt G. Goering, Stephanie M. Rice, Mark O'Neil-Johnson, Gary R. Eldridge
Institution: Sequoia Sciences (United States)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2420526936