Translational Meta-analytical Methods to Localize the Regulatory Patterns of Neurological Disorders in the Human Brain.
Year: 2015
Type: article
Abstract: The task of mapping neurological disorders in the human brain must be informed by multiple measurements of an individual's phenotype - neuroimaging, genomics, and behavior. We developed a novel meta-analytical approach to integrate disparate resources and generated transcriptional maps of neurological disorders in the human brain yielding a purely computational procedure to pinpoint the brain location of transcribed genes likely to be involved in either onset or maintenance of the neurological condition.
Source: PubMed Central
Authors: Vanessa Sochat, Maude David, Dennis P Wall
Institutions: Stanford Medicine, Stanford University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2426265068