Regulated mRNA Decay in Arabidopsis: A global analysis of differential control by hormones and the circadian clock
Year: 2010
Type: report
Abstract: The long-term goal of this research was to better understand the influence of mRNA stability on gene regulation, particularly in response to hormones and the circadian clock. The primary aim of this project was to examine this using DNA microarrays, small RNA analysis and other approaches. We accomplished these objectives, although we were only able to detect small changes in mRNA stability in response to these stimuli. However, the work also contributed to a major breakthrough allowing the identification of small RNAs on a genomic scale in eukaryotes. Moreover, the project prompted us to develop a new way to analyze mRNA decay genome wide. Thus, the research was hugely successful beyond our objectives.
DOI: 10.2172/973679
Authors: Univ. of Delaware, Newark, DE (United States), Pamela Green, USDOE
Institution: University of Delaware
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
Funder: U.S. Department of Energy
OpenAlex ID: W2432439583