Work

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Year: 2016

Type: article

Source: Nature Structural & Molecular Biology

DOI: 10.1038/nsmb.3245

Authors: Guorui Yao, Sicai Zhang, Stefan Mahrhold, Kwok-ho Lam, Daniel Stern, Karine Bagramyan, Kay Perry, Markus Kalkum, Andreas Rummel, Min Dong, Rongsheng Jin

Institutions: University of California, Irvine, Boston Children's Hospital, Harvard University, Medizinische Hochschule Hannover, Robert Koch Institute, City Of Hope National Medical Center, City of Hope, Beckman Research Institute, Argonne National Laboratory, Cornell University

Language: English

Topic: Botulinum Toxin and Related Neurological Disorders

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Center for Research Resources

Awards: Structural and functional studies of botulinum neurotoxin, Pixel Array Detector for X-ray Crystallography, Structural mechanism for recognition of host receptor by botulinum neurotoxin A, Diagnostic assay systems for Botulinum Neurotoxins, NE-CAT Center for Advanced Macromolecular Crystallography, Integrated Epithelial and Muscosal Biology, Biology and Engineering of Botulinum Neurotoxins.

OpenAlex ID: W2435601802

FWCI: 10.56

Cites: 45

Cited by: 116

Related to: 10