Work

Proteomic analysis of colon and rectal carcinoma using standard and customized databases

Year: 2015

Type: data-paper

Abstract: Understanding proteomic differences underlying the different phenotypic classes of colon and rectal carcinoma is important and may eventually lead to a better assessment of clinical behavior of these cancers. We here present a comprehensive description of the proteomic data obtained from 90 colon and rectal carcinomas previously subjected to genomic analysis by The Cancer Genome Atlas (TCGA). Here, the primary instrument files and derived secondary data files are compiled and presented in forms that will allow further analyses of the biology of colon and rectal carcinoma. We also discuss new challenges in processing these large proteomic datasets for relevant proteins and protein variants.

Source: Scientific Data

DOI: 10.1038/sdata.2015.22

Authors: Robbert J.C. Slebos, Xia Wang, Xiaojing Wang, Bing Zhang, David L. Tabb, Daniel C. Liebler

Institutions: Vanderbilt University, Vanderbilt-Ingram Cancer Center, University of Cincinnati

Language: English

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490