Work

Pathogenesis of human immunodeficiency virus infection and prospects for control.

Year: 1987

Type: article

Abstract: In just six years after the initial description of the acquired immunodeficiency syndrome, much has been learned about the etiologic agent, the human immunodeficiency virus. The pathogenic mechanisms utilized by this virus to infect selectively and persistently T4+ lymphocytes and monocyte/macrophages, leading to immunodeficiency and neurologic dysfunction, are slowly becoming clear. Better understanding of the pathogenesis of human immunodeficiency virus infection is essential for the rational design of therapeutic and preventive strategies to combat this deadly virus.

Source: PubMed Central

Authors: D D Ho, J C Kaplan

Institution: Cedars-Sinai Medical Center

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Award: VIRUSES, ONCOGENES, AND KAPOSI'S SARCOMA