Work

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes

Year: 2015

Type: article

Source: ACS Chemical Biology

Authors: Satyamaheshwar Peddibhotla, Pauline Fontaine, Chi K. Leung, Patrick Maloney, Paul M. Hershberger, Ying Wang, Michelle S. Bousquet, Hendrik Luesch, Arianna Mangravita-Novo, Anthony B. Pinkerton, Layton H. Smith, Siobhan Malany, Keith Choe

Institutions: Sanford Burnham Prebys Medical Discovery Institute, University of Florida

Language: English

Topic: Helminth infection and control

Subfield: Small Animals

Field: Veterinary

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Yale University, Florida Department of Health, National Institutes of Health, National Institute of Neurological Disorders and Stroke, Division of Integrative Organismal Systems

Awards: A high throughput screen for inhibitors of nematode detoxification genes, G5015177126, G7697078838

OpenAlex ID: W246167980

FWCI: 1.984

Cites: 48

Cited by: 12

Related to: 10