The role of ESCRT proteins and phosphoinositides in MVE biogenesis, endocytic trafficking and disease
Year: 2009
Type: dissertation
Abstract: In order to survive, eukaryotic cells must be in constant communication with the exterior environment. Not only is the cell dependent on the uptake of nutrients and the transmission of metabolic, neuronal and proliferative signals, it also has to protect itself and the organism from microbial invasion. As the vital barrier and the primary interface of the cell with its exterior environment, the limiting membrane is important for the detection of and accurate response to extracellular signals (e.g. from receptors, ions, nutrients and pathogens) and the entry of molecules into the cell, thereby contributing to long-term cell survival.
Author: Susanne Stuffers
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2462768526