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Incidental Findings of Bacterial Vaginosis and Other Infections in Papanicolaou Smears of HIV-infected and HIV-uninfected Adolescent Females in South Africa.

Year: 2014

Type: article

Abstract: Bacterial vaginosis (BV) is a widely prevalent infection that is associated with a range of adverse outcomes. We compared the rates of incidentally identified BV and other cervico-vaginal infections on Papanicolaou (Pap) smears of HIV-infected and HIV-uninfected adolescent females in South Africa. Cervical specimens from 50 HIV-uninfected and 32 HIV-infected sexually active South African adolescent females age 17-21 were collected and analyzed in accordance with the Bethesda system. We found a high overall prevalence of BV (54.9%) in our cohort. While previous research has found an increased prevalence of BV among HIV-infected women, the difference in the prevalence of BV between our HIV-infected group (62.5%) and HIV-uninfected group (50.0%) was not found to be statistically significant. The high rate of BV in both of these groups has significant implications for their risk of HIV acquisition and/or transmission in addition to other associated risks of BV. Given that the Pap smear is specific in incidentally diagnosing BV, it may be utilized as a screening method for BV in the adolescent population.

Source: PubMed