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Superoxide anion production and superoxide dismutase and catalase activities in Coxiella burnetii

Year: 1983
Type: article
Abstract: Coxiella burnetii was examined for superoxide anion (O2-) production and superoxide dismutase and catalase activities. The organism generated O2- at pH 4.5 but not at pH 7.4. The rickettsia displayed superoxide dismutase activity distinguishable from that of the host cell (L-929 mouse fibroblast). Catalase activity was maximal at pH 7.0 and diminished at pH 4.5. These enzymes may account, in part, for the ability of this obligate intracellular parasite to survive within phagocytes.
Language: English
Subfield: Parasitology
Open Access status: bronze
OpenAlex ID: W2105248129
FWCI: 1.662
Cites: 35
Cited by: 45
Related to: 10