Comparison of Bowel Preparation Depending on Completion Time of Polyethylene Glycol Ingestion and Start Time of Colonoscopy
Year: 2010
Type: article
Study design: Observational Study
Abstract: Background/Aims: Polyethylene glycol (PEG) solution is the most widely used bowel preparation agent for colonoscopy because of its safety and efficacy in colon cleansing.It has been hypothesized that the timing of colon preparation may influence the quality of colon cleansing, and therefore affect the diagnostic yield of colonoscopy.The aim of this study was to determine the optimal interval of time between complete ingestion of PEG and performing colonoscopy.Methods: We prospectively enrolled 1,355 patients who had undergone a PEG-based bowel preparation on the day of colonoscopy in 11 tertiary hospitals in Korea between March 2008 and February 2009.All colonoscopies were performed in the afternoon.The start time of PEG ingestion, completion time of PEG ingestion, dose of PEG ingested, start time of colonoscopy, and the quality of bowel cleansing were recorded.Results: There was no difference of cleansing quality of bowel preparation between three groups of less than 7 hours of elapsed time (2≤ and <3 hours, 3≤ and <5 hours, 5≤ and <7 hours).However, group of more than 7 hours of elapsed time presented poor cleansing quality than others (P<0.01).Conclusions: If >7 hours elapses after ingestion of PEG, the quality of bowel preparation is poor.Therefore, depending on the time colonoscopy is scheduled, the start time of PEG ingestion may need to be adjusted.(Intest Res 2010;8:24-29)
Source: Intestinal Research
Institutions: Kangbuk Samsung Hospital, Sungkyunkwan University, Dankook University Hospital, Dankook University, Ewha Womans University, Ewha Womans University Seoul Hospital, Soonchunhyang University, Soonchunhyang University Hospital Cheonan, Samsung Seoul Hospital, Hanyang University Seoul Hospital, Hanyang University, Yonsei University, Wonju Severance Christian Hospital, Yonsei University Mirae Campus, Kosin University, Hallym University, Yeungnam University Medical Center, Yeungnam University College, Yeungnam University, Korea University, Korea University Medical Center
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2108661141