Análise morfométrica dos túbulos seminíferos de camundongos suplementados com óleo de alho
Year: 2015
Type: article
Abstract: Introduction: Garlic (Allium sativum) is widely used in cooking and in the treatment and prevention of various diseases. The literature lacks for toxicity and the effects that excessive consumption of garlic can cause the male reproductive system. The garlic oil comprises volatile compounds in their bulbs. This study aims to evaluate the morphometric of the seminiferous tubules with garlic oil supplemented mice. Methods: We treated 32 BALB/c mice divided into 4 experimental groups: 1,4 mg/kg (therapeutic dose); 14 mg/kg; 28 mg/kg; and control incorporated into feed meal. After the experimental period, the animals were sacrificed and had their testes removed and weighed. Following standard procedures for preparation of histological slides, we measured the thickness of the seminiferous tubules through the distance from the wall to the lumen. Results and Discussion: Through the measurements of the seminiferous tubules, no statistical differences could indicate changes in these structures in animals supplemented with garlic oil compared with the control group were observed. From this study it is concluded that supplemented mice with garlic oil, in different doses, for a period of 35 days, showed no morphometric changes in the seminiferous tubules which could indicate toxicity.
Source: Revista Fitos
Institution: Universidade do Vale do Itajaí
Language: Spanish
Topic: Garlic and Onion Studies
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2254198269