Work

Optimization of pH and temperature in the process of bioconversion of glucose to 2, 5-diketo-D-gluconic acid

Year: 2002

Type: article

Abstract: The process of bioconversion of glucose to 2,5-diketo-D-gluconic acid by Erwinia citreus is the first step of a two-stage fermentation process to ketogluconic acid. This work presents the optimization of pH and temperature for biomass growth. A two-level factorial experimental design with central point was used. The evolutionary operation method (EVOP) was used to determine optimal operating conditions. A numerical algorithm explained below determined maximum specific growth rate, as a trial function. Optimal operating conditions were found to be pH 5.5 and the temperature 32 °C.

Source: Chemical and Biochemical Engineering Quarterly

Authors: Bruno Zelić, Nediljko Pavlović, V. Delić, B. Vasic-Racki

Language: English

Topic: Microbial metabolism and enzyme function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W2467766018

FWCI:

Cites:

Cited by: 2

Related to: 10