Work

Cell behaviors and dynamics during angiogenesis

Year: 2016

Type: review

Abstract: Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.

Source: Development

DOI: 10.1242/dev.135616

Authors: Charles Betz, Anna Lenard, Heinz-Georg Belting, Markus Affolter

Institution: University of Basel

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: National Science Foundation, Novartis, Krebsliga Schweiz

Awards: G1360234231, G4991972128, G6806805826