Work

The calcium paradox - What should we have to fear?

Year: 2014

Type: article

Abstract: The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellular injury in the calcium paradox intercellular connection maintained only by nexus seems to have a key role in cellular fragmentation. The addition of small concentrations of calcium, calcium channel blockers, and hyponatraemia hypothermia are important to prevent any cellular damage during reperfusion solutions with physiological concentration of calcium.

Source: Brazilian Journal of Cardiovascular Surgery

DOI: 10.5935/1678-9741.20140054

Authors: Marcos Aurélio Barboza de Oliveira, Antônio Carlos Brandi, Carlos Alberto dos Santos, Paulo Henrique Husseni Botelho, José Luís Lasso Cortez, Gilberto Goissis, Domingo Marcolino Braile

Institutions: Faculdade de Medicina de São José do Rio Preto, Hospital de Base, Santa Casa de Votuporanga, Braile Biomédica (Brazil)

Language: English

Topic: Cardiac Ischemia and Reperfusion

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2205773446

FWCI: 0.22

Cites: 46

Cited by: 10

Related to: 10