Sensitivity of knockout cells to MMC, IR, MMS and UV
Year: 2011
Type: other
Abstract: Copyright information:Taken from "Repression of mutagenesis by Rad51D-mediated homologous recombination"Nucleic Acids Research 2006;34(5):1358-1368.Published online 6 Mar 2006PMCID:PMC1390685.© The Author 2006. Published by Oxford University Press. All rights reserved The AA8 parental cell line was used to create two conditional knockout clones, 51D1Lox and 51D2Lox e.g. (B), which have undergone independent gene targeting in the second allele of . The 51D1 cells were stably transfected with the hamster gene to produce corrected clones 51D1.3 and 51D1.4 e.g. (A). Each data point represents the mean of two or three experiments; error bars are SEM. () MMC survival curves; note log scale for dose. () γ-ray survival curves. () MMS survival curves. () UV-C survival curves.
Source: Figshare
Authors: Hinz, John M., Tebbs, Robert S., Wilson, Paul F., Nham, Peter B., Salazar, Edmund P., Nagasawa, Hatsumi, Salustra S. Urbin, Bedford, Joel S., Thompson, Larry H.
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6939675353