Year: 2016
Type: book-chapter
Abstract: Positron emission tomography (PET) plays important roles in cancer diagnosis, neuroimaging, and molecular imaging research. However potential points remain for which big improvements could be made, including spatial resolution, sensitivity, and manufacturing costs. Depth-of-interaction (DOI) measurement in the radiation sensor will be a key technology to get any significant improvement in sensitivity while maintaining high spatial resolution. We have developed four-layered DOI detectors based on our original light-sharing method. DOI measurement also has a potential to expand PET application fields because it allows for more flexible detector arrangement. As an example, we are developing the world’s first, open-type PET geometry, “OpenPET,” which is expected to lead to PET imaging during treatment. The DOI detector itself continues to evolve with the help of recently developed semiconductor photodetectors, often referred to as silicon photomultipliers (SiPMs). We are developing a SiPM-based DOI detector “X’tal cube” to achieve sub-mm spatial resolution, which is reaching the theoretical limitation of PET imaging. Innovation of SiPMs encourages our development of PET/MRI, which is attracting great notice in terms of smaller radiation exposure and better contract in soft tissues compared with current PET/CT.
Source: Springer eBooks
Author: Taiga Yamaya
Institution: National Institute of Radiological Sciences
Language: English
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W2472551037