Role of Repair Enzymes - Damage Control of DNA From Ageing pans
Year: 2016
Type: article
Abstract: DNA is a precious molecule. It encodes vital information about cellular content and function. DNA repair maintains genomic stability and the loss of DNA repair capacity results in genetic instability that may lead to a decline of cellular function. The accumulation of DNA damage in multicellular organisms is linked to aging. To prevent deleterious effects, damage is balanced by repair pathways. Cells evolved a number of mechanisms to detect and repair the various types of damage that can occur to DNA, no matter whether this damage is caused by the environment or by errors in replication. The present review summarizes the various issues of DNA damage and their repair mechanism to overcome from aging.
Authors: Shilpa Singh, Mitasha Purohit
Institution: Vikram University
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W2474542895