Наследственные характеристики BRCA1 5382insC/сhek2/blm-ассоциированного рака молочной железы
Year: 2014
Type: article
Study design: Observational Study
Abstract: The hereditary breast cancer (HBC) occurs in 5–10 % of all cases of breast cancer. The mutations in the genes of high penetrance – BRCA1, BRCA2 is mainly the reason HBC. In the study presented the features of HBC (age of onset of the disease, cancer family history, primary tumor process multiple character). Depending on the presence of mutations BRCA1 5382insC, BLM, CHEK2 carried out a comparative analysis of the occurrence of hereditary characteristics in breast cancer patients.
Source: Siberian Journal of Oncology
Author: Е.М. Бит-Сава
Language: Russian
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2475719715