Year: 2012
Type: book
Abstract: Clearance mechanisms Enzymes contribuƟng to clearance CYP UGT FIGURE 2-4.Clearance mechanism of the top 200 drugs prescribed in the United States in 2002 and the enzymes involved in their metabolism (data after [56]).Individual pie charts are (counterclockwise from top left): listed clearance mechanisms (from http://www.rxlist.com);listed enzymes contributing to clearance for metabolized drugs; proportion of UDP-glucuronosyltransferase (UGT) substrates in the top 200 metabolized by each member of that subfamily listed; and the proportion of cytochrome P450 (CYP) substrates in the top 200 metabolized by each member of that subfamily listed.10.
Source: Wiley eBooks
Authors: Nicholas Bodor, Peter Buchwald
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2475974239