Work

Inflammatory bowel disease related innate immunity and adaptive immunity.

Year: 2016

Type: article

Abstract: Inflammatory bowel disease (IBD) is a chronic nonspecific intestinal inflammatory disease, including ulcerative colitis (UC) and Crohn's disease (CD). Its pathogenesis remains not yet clear. Current researchers believe that after environmental factors act on individuals with genetic susceptibility, an abnormal intestinal immune response is launched under stimulation of intestinal flora. However, previous studies only focused on adaptive immunity in the pathogenesis of IBD. Currently, roles of innate immune response in the pathogenesis of intestinal inflammation have also drawn much attention. In this study, IBD related innate immunity and adaptive immunity were explained, especially the immune mechanisms in the pathogenesis of IBD.

Source: Europe PMC (PubMed Central)

Authors: Yuan Huang, Zhonge Chen

Institutions: Beijing Tsinghua Chang Gung Hospital, Tsinghua University, Second Affiliated Hospital of Nanchang University

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2476770332

FWCI: 13.63

Cites: 44

Cited by: 128

Related to: 10