Work

Comment on “Multiple repressive mechanisms in the hippocampus during memory formation”

Year: 2016

Type: letter

Abstract: Cho et al. (Reports, 2 October 2015, p. 82) report that gene repression after contextual fear conditioning regulates hippocampal memory formation. We observe low levels of expression for many of the top candidate genes in the hippocampus and robust expression in the choroid plexus, as well as repression at 4 hours after contextual fear conditioning, suggesting the inclusion of choroid plexus messenger RNAs in Cho et al. hippocampal samples.

Source: Science

DOI: 10.1126/science.aaf1288

Authors: Rebecca S. Mathew, Hillary Mullan, Jan Krzysztof Blusztajn, Maria K. Lehtinen

Institutions: Howard Hughes Medical Institute, Harvard University, Boston Children's Hospital, Boston University

Language: English

Topic: Memory and Neural Mechanisms

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green