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The long terminal repeat negative control region is a critical element for insertional oncogenesis after gene transfer into hematopoietic progenitors with Moloney murine leukemia viral vectors

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Year: 2016
Type: article
Source: Gene Therapy
DOI: 10.1038/gt.2016.51
Authors: Y Ikawa, T Uchiyama, G J Jagadeesh, F Candotti
Institutions: National Human Genome Research Institute, Kanazawa University Hospital, National Research Institute for Child Health and Development, Centre Hospitalier Universitaire Vaudois
Language: English

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Université de Lausanne, National Institutes of Health, Japan Society for the Promotion of Science, National Human Genome Research Institute
Award: Establishment of Baboon envelope pseudotyped LV vector system to maintain the stemness in stem cell gene therapy.
OpenAlex ID: W2499781207
FWCI:
Cites: 22
Cited by: 2
Related to: 10
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