In vivo trials on the therapeutic effects of encapsulated Artemisia annua and Artemisia afra
Year: 2016
Type: article
Study design: Clinical Trial
Abstract: This trial took place in the province of Katanga in the RDCongo and was handled in two parts 82 volunteers suffering from malaria were treated during 7 days with capsules containing powdered leaves of Artemisia annua from Luxembourg (AAL) or from Burundi (AAB) and Artemisia afra ( AAF ) . Total dose for AAL was 15 gr, for AAB 7.5 gr and for AAF 7.5 gr. Despite these low doses all patients were free of fever after 2 days and 85% were free of parasites after 7 days for AAL, 76% for AAB and 40% for AAF. 44 volunteers carrying trophozoites were treated with capsules containing Artemisia afra leaf powder from Burundi. The total dose of Artemisia afra powder administered over 10 days was 20.gr. In order to better understand the prophylactic and therapeutic effect of Artemisia herbal medicine on malaria infection it is important to assess the CD4 count and gametocyte carriage before and after treatment. It was found that on day 10 the CD4 count had on the average increased by 20% and the trophozoite carriage was reduced to zero except in a few rare cases
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2499969840