Work

Multiplexed Molecular Diagnostics for Respiratory, Gastrointestinal, and Central Nervous System Infections

Year: 2016

Type: review

Abstract: The development and implementation of highly multiplexed molecular diagnostic tests have allowed clinical microbiology laboratories to more rapidly and sensitively detect a variety of pathogens directly in clinical specimens. Current US Food and Drug Administration-approved multiplex panels target multiple different organisms simultaneously and can identify the most common pathogens implicated in respiratory viral, gastrointestinal, or central nervous system infections. This review summarizes the test characteristics of available assays, highlights the advantages and limitations of multiplex technology for infectious diseases, and discusses potential utilization of these new tests in clinical practice.

Source: Clinical Infectious Diseases

DOI: 10.1093/cid/ciw494

Authors: Kimberly E. Hanson, Marc Roger Couturier

Institutions: University of Utah, ARUP Laboratories (United States)

Language: English

Topic: Bacterial Identification and Susceptibility Testing

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases