Work

Cardiac Pacemaker Development from a Tertiary Heart Field

Year: 2016

Type: book-chapter

Abstract: Rhythmic heartbeats are paced by electrical impulses that are autonomously generated by cardiac pacemaker cells. This chapter briefly summarizes our recent findings regarding the embryonic origin of and molecular mechanism delineating cardiac pacemaker cells, showing that pacemaker cells are physically segregated and molecularly programmed, in a tertiary heart field, prior to the onset of cardiac morphogenesis.

Source: Springer eBooks

DOI: 10.1007/978-4-431-54628-3_39

Authors: Michael Bressan, Gary Liu, Jonathan D. Louie, Takashi Mikawa

Institution: University of California, San Francisco

Language: English

Topic: Congenital heart defects research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funder: National Institutes of Health

OpenAlex ID: W2505444785