Year: 2006
Type: article
Study design: Observational Study
Abstract: was developed and validated to measure the FD of human brain WM interior structure, WM surface and WM general structure simultaneously.The results indicated that the method was accurate in quantifying 3D brain WM structures and sensitive in detecting age-related degeneration of these structures.Finally, a cross-sectional study was conducted to investigate WM complexity changes in normal aging.WM FDs of old people were found to be significantly smaller than those of young people, suggesting that WM structural complexity declined with normal aging.These findings provided new information in describing brain WM structural complexity, which might in the future serve as an objective diagnostic index or as a predictive parameter for neurological diseases.This method might be used for longitudinal studies to evaluate the effect of disease or aging on WM.xviii
Author: Luduan Zhang
Institution: Case Western Reserve University
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2507362174