Work

High-Throughput Microfluidic Device for Circulating Tumor Cell Isolation from Whole Blood.

Year: 2015

Type: conference-paper

Abstract: Circulating tumor cells (CTCs) are promising markers to determine cancer patient prognosis and track disease response to therapy. We present a multi-stage microfluidic device we have developed that utilizes inertial and Dean drag forces for isolating CTCs from whole blood. We demonstrate a 94.2% ± 2.1% recovery of cancer cells with our device when screening whole blood spiked with MCF-7 GFP cells.

Source: PubMed

Authors: Daniel K Yang, Serena Leong, Lydia L Sohn

Institution: University of California, Berkeley

Language: English

Topic: Microfluidic and Bio-sensing Technologies

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute

Award: Isolating Circulating Tumor Cells