Work

Solid-phase synthesis and fluorine-18 radiolabeling of cycloRGDyK

Year: 2016

Type: article

Abstract: )) and subsequent radiolabeling yield of 14 ± 2% (decay corrected, n = 4). This approach is generally applicable to the development of an automated process for the synthesis of cyclic radiolabeled peptides for positron emission tomography (PET).

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c6ob01636g

Authors: Ryan A. Davis, Kevin Lau, Sven H. Hausner, Julie L. Sutcliffe

Institution: University of California, Davis

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: U.S. Department of Energy, National Institutes of Health, Office of Science, National Cancer Institute

Awards: RADIOCHEMISTRY RESEARCH AND TRAINING: UC DAVIS (R2@UCDAVIS), RADIOCHEMISTRY RESEARCH AND TRAINING: UC DAVIS (R2@UCDAVIS), avb6-directed molecular imaging and therapy, G7028828880