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DLI Therapy Using T-Rapa Cells: Graft-Versus-Lymphoma and GvHD Effects

Year: 2016
Type: article
Abstract: DLI therapy has limited efficacy and substantial GVHD risks. IL-4 polarized, rapamycin-resistant CD4+ (T-Rapa) cells were safe when administered as pre-emptive DLI (Fowler, Blood, 2013). Here, we evaluated the clinical GVL and GVHD effects of T-Rapa DLI for disease relapse or progression.
DOI: 10.1016/j.bbmt.2015.11.919
Authors: Monalisa Ghosh, Bazetta Blacklock Schuver, Ellen Carroll, Hanh Khuu, David F. Stroncek, Steven Z. Pavletic, Ronald Gress, David Halverson, Daniel Fowler
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2510232247
FWCI:
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Related to: 10