Procedures for risk-stratification of lung cancer using buccal nanocytology
Year: 2016
Type: article
Abstract: Lung cancer is the leading cause of cancer deaths in the U.S. with survival dramatically depending on stage at diagnosis. We had earlier reported that nanocytology of buccal cells can accurately risk-stratify smokers for the presence of early and late-stage lung cancer. To translate the technique into clinical practice, standardization of operating procedures is necessary to consistently yield precise and repeatable results. Here, we develop and validate simple, robust, and easily implementable procedures for specimen collection, processing, etc. in addition to a commercially-viable instrument prototype. Results of this work enable translation of the technology from academic lab to physicians' office.
Source: Biomedical Optics Express
DOI: 10.1364/boe.7.003795
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,913
Awards: G269951890, High-throughput molecular-specific cell nanocytology for cancer screening, G4840190321, Buccal Nanocytological Risk Stratification to Personalize Lung Cancer Screening, COLORECTAL CANCER (CRC) SCREENING VIA RECTAL NANOCYTOLOGY, SBIR Phase I: Partial Wave Spectroscopic (PWS) Microscopy: an Early Screening for Lung Cancer, G9000177991
OpenAlex ID: W2511568205